What is 5-Amino-1-MQ? | How Does 5-Amino-1-MQ Work?
- james brown
- 5 days ago
- 2 min read
What is 5-Amino-1-MQ?
5-Amino-1-MQ (5-Amino-1-methylquinolinium) is a small-molecule NNMT inhibitor studied for its effects on fat metabolism, cellular energy, and longevity pathways. By blocking the activity of the enzyme NNMT (Nicotinamide N-methyltransferase), 5-Amino-1-MQ helps preserve NAD⁺ levels — a critical coenzyme for mitochondrial function and cellular repair.
How Does 5-Amino-1-MQ Work?
1. Inhibits NNMT
NNMT consumes NAD⁺ precursors and contributes to fat storage. By inhibiting NNMT, 5-Amino-1-MQ helps conserve NAD⁺, leading to improved cellular energy and metabolism.
2. Boosts NAD⁺ Levels
Higher NAD⁺ levels support mitochondrial health, DNA repair, and energy production — all central to performance and longevity studies.
3. Accelerates Fat Metabolism
Research suggests 5-Amino-1-MQ reduces fat storage while enhancing lipid breakdown, making it a subject of interest in obesity and metabolic studies.
4. Supports Insulin Sensitivity
By improving glucose handling, 5-Amino-1-MQ may play a role in research related to insulin resistance and metabolic syndrome.
5. Cognitive & Longevity Pathways
Since NAD⁺ is tied to cellular resilience and brain health, preserving it through NNMT inhibition may support cognitive performance and anti-aging research.
Key Research Areas for 5-Amino-1-MQ
Fat metabolism & weight regulation
NAD⁺ preservation & energy support
Insulin sensitivity & glucose control
Cellular repair & DNA health
Longevity & cognitive function
Why 5-Amino-1-MQ is Unique
Unlike peptides that work through receptor activation, 5-Amino-1-MQ targets an enzyme bottleneck in metabolism (NNMT). This makes it an innovative tool for research into fat utilization, mitochondrial health, and NAD⁺ biology.
FAQ: How Does 5-Amino-1-MQ Work?
Q: What does 5-Amino-1-MQ inhibit?A: It inhibits NNMT, preserving NAD⁺ levels and supporting cellular energy balance.
Q: What are the main research benefits?A: Fat metabolism, NAD⁺ boosting, insulin sensitivity, and longevity support.
Q: Is 5-Amino-1-MQ approved for human use?A: No. It is a research compound only, not approved for human or medical consumption.
Disclaimer
This content is for educational and research purposes only. 5-Amino-1-MQ is not approved for human consumption and is intended strictly for laboratory research.
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