Inside the Fat Attack Stack: How Multi-Pathway Research Compounds Work Together
- james brown
- Sep 14
- 2 min read
The Fat Attack Stack:
When it comes to studying fat metabolism, no single pathway tells the full story. That’s why researchers are turning to combinations of peptides that address fat storage, energy expenditure, and metabolic flexibility all at once. The Fat Attack Stack is built on that idea — five research-grade compounds that complement one another to explore fat-burning potential from multiple angles.
The Core Compounds
1. Retatrutide
Multi-agonist peptide that acts on GLP-1, GIP, and glucagon pathways.
Supports appetite regulation and energy expenditure in research.
Considered one of the most advanced compounds in ongoing studies.
2. Tesamorelin
A growth hormone–releasing peptide (GHRH analog).
Stimulates natural GH production → downstream IGF-1 and enhanced lipolysis.
Studied extensively for its ability to reduce visceral adipose tissue.
3. MOTS-c
Often called an “exercise mimetic.”
Activates AMPK, a key regulator of energy and fat metabolism.
Promotes mitochondrial biogenesis, glucose utilization, and metabolic resilience.
4. SLU-PP-332
Investigational SARM-like compound that promotes fat oxidation.
May enhance endurance and metabolic rate in research settings.
Complements GH and mitochondrial pathways with a unique mechanism.
5. 5-Amino-1-MQ
Inhibits NNMT (Nicotinamide N-methyltransferase).
Preserves NAD⁺ precursors → more fuel for mitochondrial energy.
Research suggests potential to boost metabolism while protecting lean muscle.
Why Stack Instead of Single Compounds?
Fat metabolism is multi-dimensional. Appetite control alone won’t address mitochondrial efficiency. GH stimulation alone won’t optimize NAD⁺ availability. By stacking, researchers can:
Hit Multiple Pathways → GH axis, AMPK activation, GLP-1 signaling, NAD⁺ preservation.
Create Synergy → one compound creates demand, another ensures supply, another optimizes efficiency.
Reduce Gaps → single-compound research often shows plateau effects; stacking minimizes blind spots.
The Synergy Effect
Think of it like an engine:
Retatrutide acts as the governor → appetite and calorie intake regulation.
Tesamorelin revs the system → GH-driven fat mobilization.
MOTS-c upgrades the pistons → better mitochondrial machinery.
5-Amino-1-MQ ensures the fuel tank stays full → NAD⁺ preserved for energy.
SLU-PP-332 adds torque → ramped-up fat oxidation and endurance.
Together, the Fat Attack Stack doesn’t just push one lever — it activates the whole control board of fat metabolism research.
Research-Only Disclaimer
These compounds are for laboratory research use only.Not for human consumption. No medical claims are being made. RevPep supplies are intended solely for controlled research environments.
Comments